Common Pathogenetic Pathways in Allergic and Irritant Contact Dermatitis

Allergic and Irritant Contact Dermatitis

Wound-Related Allergic/Irritant Contact Dermatitis.

PURPOSE To provide information from a literature review about the prevention, recognition, and treatment for contact dermatitis. TARGET AUDIENCE This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES After participating in this educational activity, the participant should be better able to:1. Identify signs and symptoms o...

Cytokines and Chemokines in Irritant Contact Dermatitis

Irritant contact dermatitis is a result of activated innate immune response to various external stimuli and consists of complex interplay which involves skin barrier disruption, cellular changes, and release of proinflammatory mediators. In this review, we will focus on key cytokines and chemokines involved in the pathogenesis of irritant contact dermatitis and also contrast the differences bet...

Current concepts of irritant contact dermatitis.

Correspondence to: Dr J S C English, Consultant Dermatologist, Queen’s Medical Centre, University Hospital, Nottingham NG7 2UH, UK; john.english@ mail.qmcuh-tr.trent.nhs.uk _________________________ C ontact dermatitis is an eczematous eruption caused by external agents, which can be broadly divided into irritant substances that have a direct toxic effect on the skin (irritant contact dermatiti...

Occupational allergic and irritant contact dermatitis in workers exposed to polyurethane foam.

OBJECTIVES To evaluate sensitization to chemicals present in work environment after an outbreak of contact dermatitis in workers of vehicle equipment factory, exposed to polyurethane foam, based on 4,4'-diphenylmethane diisocyanate (MDI). MATERIAL AND METHODS From among 300 employees, 21 individuals reporting work-related skin and/or respiratory tract symptoms underwent clinical examination, ...